Evolence has been developed by the OrthoNeutrogena Aesthetics Group and is claimed to be the first of its kind positioned on the market as a collagen-based structural dermal filler. The technology has already been used in Canada, Europe, Israel and South Korea since 2004, and will now be launched in the US market following its FDA approval. FDA cautious over dermal fillers However, as the FDA is traditionally cautious with regards to the approval of non-surgical treatments such as injectable fillers, the go-ahead has taken significantly longer than in other global markets. "We are entering the US aesthetic space with a differentiated dermal filler designed for optimal patient outcomes," said Annie Heremans, company vice president. The product will be introduced in cosmetic clinics throughout the US during the second half of 2008, in accordance with requirements for specific physician training necessary to ensure the safety of the procedure. The collagen used in the procedure is, according to the company, naturally sourced porcine collagen, which is the most genetically similar to that found in human skin. Maintains skin elasticity When injected it helps to maintain and enhance the skin's strength, structure and maintain the structural support once the skin's dermal layer has been compromised by the aging process. The filler is based on Glymaterix technology, which is cross-linked with collagen using the natural sugar, D-Ribose. This technology is designed to mimic naturally occurring collagen in the skin, combining it with cross-links to ensure the durability of the procedure. Study confirms efficacy of collagen treatments Back in May, researchers at the University of Michigan undertook a comprehensive study which claimed to underline and confirm the effectiveness of collagen-based anti-aging treatments. The research team has published a report in the current issue of Archives of Dermatology highlighting the effects that collagen collapse has on the ageing process. Likewise, the report highlights how several treatments developed over the past ten years or so have shown the potential to help prevent this collapse of collagen that leads to wrinkles. The study particularly focused on three treatments in particular - topical retinoic acid, carbon dioxide laser resurfacing and injections of cross-linked hyaluronic acid.