The ten best synthetic skincare ingredients (according to AveSeena founder)

By Simon Pitman

- Last updated on GMT

© Jonathan Storey / Getty Images
© Jonathan Storey / Getty Images

Related tags Synthetic ingredients

Synthetic ingredients have helped revolutionize the skincare space. For formulators they represent the key to both more eco-friendly and effective products.

In the second part of this article highlighting the power of synthetic ingredients, Dr. Ebru Karpuzoglu, who is an expert in the field of molecular medicine and immunology, as well as the Founder & CSO of skincare brand AveSeena, highlights her top ten synthetic ingredients, and explains more about what the future holds.

CosmeticsDesign-USA: What would be your list of top ten preferred synthetic ingredients, and why?

Dr. Ebru Karpuzoglu: My preference for these synthetic ingredients is based on their well-documented efficacy and safety profiles. These ingredients are thoroughly researched and tested with lots of scientific articles on PubMed, making them reliable choices for addressing a wide range of skincare concerns. Additionally, they offer the ability to create products that deliver consistent results, contributing to overall skin health and beauty. When incorporated into skincare formulations, these ingredients can complement naturally derived options to achieve well-rounded and effective skincare solutions.

CDU: List of top ten synthetic ingredients

1. Niacinamide (Vitamin B3): Niacinamide is valued for its ability to improve the skin barrier, reduce redness, and tackle hyperpigmentation. It’s a versatile and well-tolerated option.

2. Hyaluronic Acid: This synthetic ingredient is renowned for its exceptional moisturizing properties. It can hold a significant amount of water, promoting hydration and skin plumpness.

3. Retinol (Vitamin A): Retinol is a powerful synthetic derivative of vitamin A. It is favored for its role in promoting skin cell turnover, reducing fine lines, and boosting collagen production.

4. Salicylic Acid: This synthetic BHA (beta hydroxy acid) is effective for exfoliating and unclogging pores, making it an excellent choice for acne-prone skin.

5. Peptides: Synthetic peptides play a vital role in stimulating collagen production, helping to firm and rejuvenate the skin.

6. Squalane: Synthetic squalane is often derived from plant sources and is appreciated for its moisturizing and emollient properties. It mimics the skin’s natural oils.

7. Vitamin C (Ascorbic Acid): Vitamin C is a synthetic ingredient that brightens the complexion, protects against free radicals, and helps in collagen synthesis.

8. Alpha Hydroxy Acids (AHAs): AHAs like glycolic and lactic acid are used for chemical exfoliation, resulting in smoother and more radiant skin.

9. Ceramides: Synthetic ceramides contribute to skin barrier repair, reducing moisture loss and enhancing overall skin health.

10. Glycolic Acid: Glycolic acid is valued for its exfoliating properties, contributing to smoother, more radiant skin. It is commonly used to address fine lines and uneven texture.

CDU: What other developments are underscoring synthetic skincare ingredients?

EK: When we consider the evolving landscape of skincare and ingredients, it’s essential to acknowledge the integral role of skin barriers, microbiome and skin immunity in this evolution. These aspects are increasingly at the forefront of skincare research and product development and the interplay between skin barriers, microbiome, skin immunity, new ingredients and evolving skincare brands are reflecting a more holistic and informed approach to skincare. As we move forward, the emphasis on preserving and fortifying these elements will continue to drive innovation and enhance the effectiveness of skincare products while keeping environmental and ethical considerations at the forefront.

CDU: Where do you see the future of synthetic ingredients going?

Dr. Ebru Karpuzoglu, MSc, PhD Molecular Medicine & Immunology, Founder & CSO of AveSeena
Dr. Ebru Karpuzoglu, MSc, PhD Molecular Medicine & Immunology, Founder & CSO of AveSeena

EK: In the evolving landscape of skincare and cosmetics, I believe the path for synthetic ingredients is paved with innovation, science and sustainability allowing for the creation of products tailored to specific skin concerns. Sustainable sourcing and manufacturing practices will play a pivotal role, giving rise to more eco-friendly synthetic ingredients.

Synthetic ingredients, known for their versatility, will be harnessed to address the unique needs of consumers. Biomimicry, which involves emulating natural skin components, will further enhance the compatibility and effectiveness of synthetic compounds.

Skincare is no longer confined to surface-level beauty but extends to holistic well-being from top to underneath from skin barriers to healthier wellness. Synthetic ingredients will align with broader health and wellness trends, aiming to improve not only the skin’s appearance but also the overall well-being of the user.

Transparency and safety will remain paramount. Consumer demand for clear, trustworthy ingredient lists will drive the industry to develop synthetic compounds with meticulous testing and safety assessments.

CDU: What role do you believe technology may play in this future?

EK: Digital technology and artificial intelligence are poised to revolutionize the industry. They will play a pivotal role in formulating precise and effective skincare solutions while enhancing the consumer experience. In sum, the future of synthetic ingredients in skincare is marked by the blend of innovation, sustainability, science and a commitment to consumer safety and well-being.

Part 1 of this two-part series can be read HERE​. 

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