The New Beauty Research Initiative (NBRI) is a collaborative programme between Amorepacific and the Department of Dermatology at Johns Hopkins launched in 2022.
Through this programme, the two organisations are conducting multifaceted research on skin ageing.
Study findings on two of Amorepacific’s proprietary ingredients were announced at the 2025 Society for Investigative Dermatology (SID) Annual Meeting held in San Diego in early May.
The SID has organised yearly meetings since its establishment in 1937. At the 82nd conference this year, more than 1,600 researchers, clinicians, and dermatologists from around the world presented over 1,200 of the latest skin research findings.
Specifically, Professor Anna Chien’s research team, a participant of NBRI, showcased the efficacy of Amorepacific’s bioflavonoid ingredient RE.D Flavonoid.
Derived from the camellia plant, RE.D Flavonoid has shown to ameliorate photoageing symptoms on the face and neck areas without causing irritation.
In particular, notable improvements were observed across major signs of skin ageing, including fine lines, skin texture, pores, radiance, and pigmentation, with significant changes in skin texture and radiance seen from the eighth week of use.
These results are based on a study involving North American consumers of diverse ethnicities who used RE.D Flavonoid for six months.
It was also found that the ingredient works by blocking signal transmission in skin ageing and inhibiting damage to collagen, which is crucial for skin elasticity.
Beyond symptom improvement
Another NBRI participant, Professor Martin Alphonse’s research team, presented on the benefits of a green tea-derived ingredient called Senomune.
A saponin component of green tea extract, Senomune was discovered to alleviate immune cell damage and inflammatory responses caused by particulate matter (PM) or pollutants in the air.
“The team also confirmed the potential for Senomune to reduce immune ageing (a natural decline in immune system function that occurs with age) and chronic inflammatory reactions due to environmental factors by balancing the metabolic functions of immune cells,” Amorepacific stated.
This study was conducted using human peripheral blood mononuclear cells (PBMC), and it was observed that the group pre-treated with Senomune had a lower stress response in immune cells to environmental hazards.
“The ongoing NBRI joint research programme, centred on skin longevity of global consumers, is a valuable opportunity to demonstrate the scientific excellence of Amorepacific’s slow-ageing skin care technology.
“We will continue to focus on researching beauty solutions aimed at activating the skin’s fundamental recovery capabilities beyond mere symptom improvement,” said Seo Byung-hwi, Director and CTO of Amorepacific R&I Center.