DermCom is the first cosmetic ingredient that uses cell to cell communication for repair deep in the skin. DermCom triggers in the skin surface cells the release of messenger compounds in order to instruct the dermis cells to activate the synthesis of collagen and elastin fibers. Based on an extract of Crocus chrysanthus bulbs, DermCom was found to stimulate the synthesis of growth factors in skin surface cells. In assays with dermis cells, these growth factor messengers strongly stimulated the synthesis of elastin. A cream with DermCom increased skin collagen and elastin already after two weeks’ application.